Is Etizolam Addictive?

What is etizolam? 

Etizolam is a derivative of thieno diazepine, which differs only slightly in chemical structure from the more well-known benzodiazepines, such as Xanax. 

If you’ve never heard of etizolam, that is because it is not FDA-approved in the United States! It is prescribed in Japan, Australia, India, and some European countries. 

However, despite not being FDA-approved in the U.S., it is still classified as a Schedule I drug—meaning it has been determined to have no accepted medical use and can put a person at high risk for developing substance use disorder—in eight states. In several additional states, it is classified as a Schedule IV controlled substance, alongside drugs such as Xanax and Valium. In all other states, it remains unscheduled. 


What is etizolam used for? 

With a chemical structure so similar to benzodiazepines, etizolam is used very similarly. Etizolam acts as a depressant on the central nervous system and is used to treat anxiety and insomnia¹.


Is etizolam addictive? 

The short answer is yes, there is a risk for substance misuse and addiction. Because it is a relatively new drug and is not FDA-approved in the U.S., many research studies and outcomes have taken place in European and Asian countries. 

A study published by UC San Diego in 2015, titled Overdose of Etizolam: The Abuse and Rise of a Benzodiazepine Analog² states, “Recent unpublished data from the American Association of Poison Control Centers in the United States has shown an incremental increase in etizolam-related cases each year since 2011, with 41 cases reported as of August 2014. There is little reported in the English literature about the toxic effects of etizolam overdose.”


Signs of etizolam abuse 

Adverse effects of etizolam use may include¹: 

  • Drowsiness
  • Sedation
  • muscle weakness and incoordination
  • Fainting
  • Headache
  • Confusion
  • Depression
  • Slurred speech
  • Visual disturbances
  • Changes in libido
  • Tremor

Etizolam Withdrawal Symptoms

Etizolam withdrawal symptoms are similar to those of benzodiazepines. These may include: 

  • Headache
  • Muscle spasms
  • Hyperventilation
  • Headache
  • Nausea or vomiting
  • Sweating 
  • Physical aches and pains
  • Racing pulse
  • Hypersensitivity to stimuli 
  • Hallucinations
  • Delirium 
  • Grand mal seizures 

It is imperative to seek medical help immediately if experiencing withdrawal symptoms from etizolam, as this type of abrupt withdrawal can be life-threatening. The safest way to stop using etizolam is to slowly taper off under the guidance of medical supervision. 

Etizolam dependence treatment at Oasis Recovery 

Oasis Recovery Center, located in the heart of Asheville, North Carolina, has helped many individuals reclaim their lives from the grips of addiction. 

Our comprehensive addiction treatment programs incorporate everything from medication-assisted treatment to psychotherapy with options such as EMDR to group activities and processing, adventure therapy, equine therapy, art therapy, and a variety of mindfulness-based holistic healing modalities including acupuncture, qi gong, yoga, meditation, and more. Clients at Oasis are supported through every step of their healing journey with our unique, individualized, impactful recovery programs. 

If you or a loved one are struggling with a dependence on etizolam, benzos, or addiction to other substances, Oasis Recovery is here to help. Reach out to us today at (828) 330-9497  or get in touch through our online contact form for more information about addiction treatment and recovery at Oasis. 


  1. U.S. Drug Enforcement Administration: Etizolam

UC San Diego: Overdose of Etizolam: The Abuse and Rise of a Benzodiazepine Analog

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